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For research use only.

Verified Samples Verified Samples in WB: Mouse spleen
Verified Samples in IHC: Human esophagus cancer, Human prostate cancer
Dilution WB 1:200-1:1000,  IHC 1:50-1:200
Isotype Rabbit IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human KLK14
Abbre KLK14
Synonyms hK14,  Kallikrein 14,  Kallikrein like protein 6,  Kallikrein-14,  Kallikrein-like protein 6,  KLK L6,  KLK-L6,  KLK14,  KLK14抗体
Swissprot
Calculated MW 29 kDa
Cellular Localization Secreted > extracellular space
Tissue Specificity Highly expressed in CNS, bone marrow and fetal liver. Also expressed in breast, thyroid, kidney, colon, pancreas, spleen, prostate, uterus, small intestine, placenta and skeletal muscle. Among 40 tissues tested, the highest expression is detected in skin followed by breast and prostate (at protein level). Expressed in stratum corneum by sweat ducts and sweat glands and detected in sweat (at protein level).
Concentration 1.40 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20℃ Valid for 12 months. Avoid freeze/thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. An additional transcript variant has been described but its full length nature has not been determined.
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