KLK7 Polyclonal Antibody (E-AB-14181)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain, Mouse kidney |
| Dilution | WB 1:500-1:2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human KLK7 |
| Abbre | KLK7 |
| Synonyms | Chymotryptic stratum corneum, KLK 7, KLK7, Kallikrein 7 (chymotryptic stratum corneum), Kallikrein related peptidase 7, Kallikrein-7, Kallikrein7, Klk7, PRSS 6, PRSS6, Protease serine 6, SCCE, Serine protease 6, Signal protein, Stratum corneum chymotrypt, hK 7, hK7, hSCCE |
| Swissprot | |
| Calculated MW | 28 kDa |
| Cellular Localization | Secreted. In ovarian carcinoma, secreted and also observed at the apical membrane and in cytoplasm at the invasive front. |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. |
Other Clones
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Other Formats
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Unconjugated
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