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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human thyroid cancer
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human KLK8
Abbre KLK8
Synonyms BSP1,  Brain serine protease 1,  HNP,  HPN,  KLK 8,  KLK8,  KLK8 protein type 1,  KLK8 protein type 2,  Kallikrein 8 (neuropsin/ovasin),  Kallikrein related peptidase 8,  Kallikrein-8,  Kallikrein8,  Klk8,  Neuropsin,  Neuropsin type 1,  Neuropsin type 2,  hK8,  included,  neuropsin type 1
Swissprot
Cellular Localization Secreted. Cytoplasm. Shows a cytoplasmic distribution in the keratinocytes.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
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Unconjugated

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