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For research use only.

Verified Samples Verified Samples in WB: Human brain
Verified Samples in IHC: Human ovarian cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human LBR
Synonyms DHCR 14B,  DHCR14B,  Integral nuclear envelope inner membrane protein,  LBR,  LMN 2R,  LMN2R,  Lamin-B receptor,  MGC9041,  PHA,  PRO0650
Swissprot
Calculated MW 71 kDa
Cellular Localization Nucleus inner membrane.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction,  Tags and Cell Markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene belongs to the ERG4/ERG24 family.It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane.It may mediate interaction between chromatin and lamin B.Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia.Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Other Clones

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Unconjugated

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