LTA4H Polyclonal Antibody (E-AB-15180)
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For research use only.
| Verified Samples |
Verified Samples in WB: Human brain Verified Samples in IHC: Human esophagus cancer |
| Dilution | WB 1:200-1:1000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human LTA4H |
| Abbre | LTA4H |
| Synonyms | FLJ17564, LKHA4, LTA-4 hydrolase, LTA4, LTA4 hydrolase, LTA4H, Leukotriene A(4) hydrolase, Leukotriene A-4 hydrolase, Leukotriene A4 hydrolase |
| Swissprot | |
| Calculated MW | 69 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein. |
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