LXR alpha Polyclonal Antibody (E-AB-70218)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Mouse liver, Rat kidney |
| Dilution | IHC 1:400-1:1500 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse LXRα |
| Abbre | LXR alpha |
| Synonyms | LXR a, LXRA, Liver X receptor alpha, NR1H3, Nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR alpha, Oxysterols receptor LXR-alpha, RLD 1, RLD1 |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 0.53 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | NR1H3,also known as LXRA,is a liver X receptors,which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function,controlling transcriptional programs involved in lipid homeostasis and inflammation. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor,then participates in regulating expression of target genes containing LXR response elements. |
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