MAD1L1 Polyclonal Antibody (E-AB-10440)
For research use only.
| Verified Samples |
Verified Samples in WB: Hela, 231, HepG2, Raji |
| Dilution | WB 1:500-1:2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MAD1L1 |
| Abbre | MAD1L1 |
| Synonyms | HsMAD1, MAD1, MAD1 mitotic arrest deficient like 1 (yeast), MAD1-like protein 1, MAD1L1, MD1L1, Mitotic arrest deficient 1, Mitotic arrest deficient 1-like protein 1, Mitotic checkpoint MAD1 protein homolog, Mitotic spindle assembly checkpoint protein MAD1, P, hMAD1 |
| Swissprot | |
| Calculated MW | 83 kDa |
| Cellular Localization | Nucleus. Chromosome>centromere>kinetochore. Cytoplasm>cytoskeleton>microtubule organizing center>centrosome. Cytoplasm>cytoskeleton>spindle. From the beginning to the end of mitosis, it is seen to move from a diffusely nuclear distribution to the centrosome, to the spindle midzone and finally to the midbody. Colocalizes with NEK2 at the kinetochore. |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts witHuman, MouseAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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