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For research use only.

Verified Samples Verified Samples in IHC: Human brain
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human MAGEL2
Abbre MAGEL2
Synonyms MAGE-like 2,  MAGE-like protein 2,  MAGEL2,  Mage-l2,  NDNL1,  Necdin like protein 1,  PWLS,  Protein nM15,  melanoma antigen-like gene 2,  nM15,  necdin-like 1,  ns7
Swissprot
Cellular Localization Cytosol, Endosome, early Endosome, Nucleus.
Concentration 0.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Other Clones

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Unconjugated

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