MANF Polyclonal Antibody (E-AB-16174)

For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human lung cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human MANF |
Abbre | MANF |
Synonyms | ARMET, ARMET protein, ARP, Arginine rich mutated in early stage tumors, Arginine rich protein, Arginine-rich protein, MANF, MGC142148, MGC142150, Manf, Mesencephalic astrocyte derived neurotrophic factor, Mesencephalic astrocyte-derived neurotrophic factor, Protein A |
Swissprot | |
Cellular Localization | Secreted. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related. |
Other Clones
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Other Formats
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Unconjugated
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