MAP1LC3B Monoclonal Antibody (E-AB-22132)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human brain |
| Dilution | IHC 1:100-200 |
| Isotype | IgG |
| Host | Mouse |
| Reactivity | Human |
| Applications | IHC-p |
| Clonality | Monoclonal |
| Immunogen | Recombinant Protein of LC3B of MAP1LC3B |
| Abbre | MAP1LC3B |
| Synonyms | ATG8F, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, LC3B, LC3II, MAP1 light chain 3 like protein 2, MAP1 light chain 3-like protein 2, MAP1A/1BLC3, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, MAP1ALC3, MAP1LC3B a, Map1lc3b, Mic |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton. Endomembrane system. Cytoplasmic vesicle>autophagosome membrane. LC3-II binds to the autophagic membranes. |
| Tissue Specificity | Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
| Clone No. | 6E4 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2. |
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Other Formats
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Unconjugated
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