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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human prostate cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human MAP1LC3C
Synonyms ATG8J,  Autophagy-related protein LC3 C,  Autophagy-related ubiquitin-like modifier LC3 C,  LC3 like protein 2,  MA,  MAP1 light chain 3 like protein 2,  MAP1 light chain 3 like protein 3,  MAP1 light chain 3-like protein 3,  MAP1A/MAP1B LC3 C,  MAP1A/MAP1B light chain 3 C
Swissprot
Cellular Localization Cytoplasm>cytoskeleton. Endomembrane system. Cytoplasmic vesicle>autophagosome membrane. LC3-II binds to the autophagic membranes.
Concentration 0.8 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Autophagy is a highly regulated bulk degradation process that plays an important role in cellular maintenance and development. MAP1LC3C is an ortholog of the yeast autophagosome protein Atg8. Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium.
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Unconjugated

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