MAP3K11 Polyclonal Antibody (E-AB-16612)
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For research use only.
| Verified Samples |
Verified Samples in WB: L-O2 Verified Samples in IHC: Human colon cancer, Human liver cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MAP3K11 |
| Abbre | MAP3K11 |
| Synonyms | 2610017K16Rik, EC 2.7.11.25, M3K11, MEKK11, MGC17114, Map3k11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Mixed lineage protein kinase 3, Mlk-3, Mlk3, PTK1, Protein tyrosine kinase PTK1, RHOE, SH3 domain containing proline rich kinase, SP |
| Swissprot | |
| Calculated MW | 93 kDa |
| Cellular Localization | Cytoplasm>cytoskeleton>centrosome. Location is cell cycle dependent. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The protein encoded by this gene is a member of the serine/threonine kinase family.This kinase contains a SH3 domain and a leucine zipper-basic motif.This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway.This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. |
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