MARK1 Polyclonal Antibody (E-AB-14680)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse heart, Mouse brain |
| Dilution | WB 1:500-1:2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MARK1 |
| Abbre | MARK1 |
| Synonyms | KIAA1477, MAP/microtubule affinity regulating kinase 1, MAP/microtubule affinity-regulating kinase 1, MARK, MARK 1, MARK1, MGC126512, MGC126513, Mark1, Serine/threonine protein kinase MARK1, Serine/threonine-protein kinase MARK1 |
| Swissprot | |
| Calculated MW | 89 kDa |
| Cellular Localization | Cytoplasm>cytoskeleton. Appears to localize to an intracellular network. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | MAP/microtubule affinity-regulating kinase 1 (MARK1) is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart. |
Other Clones
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Unconjugated
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