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For research use only.

Verified Samples Verified Samples in WB: Mouse intestinum
Dilution WB 1:500-1:2000
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB
Clonality Polyclonal
Immunogen Synthetic peptide of human MC1R
Abbre MC1R
Synonyms CMM5,  MC1-R,  MC1R,  MSH-R,  MSHR,  Melanocortin 1 receptor,  Melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor),  Melanocortin receptor 1,  Melanocyte-stimulating hormone receptor,  Melanotropin receptor,  SHEP2
Swissprot
Calculated MW 35 kDa
Cellular Localization Cell membrane.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Metabolism,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH).The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis.Two types of melanin exist: red pheomelanin and black eumelanin.Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color.Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation.Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis.This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer.Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation.
Cat.No. Product Name Sizes
E-AB-1003 Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) 500μL , 120μL , 60μL
E-AB-1043 Streptavidin(peroxidase/HRP conjugated) 500μL , 120μL , 60μL
E-AB-1194 HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed 500μL , 120μL , 1mL
E-IR-R304A Western Blot Detection Kit 50Assays
E-IR-R304B High Accuracy and Absorbability Western Blot Detection Kit 50Assays
Other Clones

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Unconjugated

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