MCL1 Polyclonal Antibody (E-AB-60044)

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For research use only.
Verified Samples |
Verified Samples in IHC: Human lung cancer, Human gastric cancer, Mouse liver Verified Samples in IF: A431 |
Dilution | IHC 1:100-1:200, IF 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC, IF |
Clonality | Polyclonal |
Immunogen | A synthetic peptide of human MCL1 (NP_068779.1). |
Abbre | MCL1 |
Synonyms | BCL2L3, EAT, MCL1, MCL1 , MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT |
Swissprot | |
Cellular Localization | Membrane. Cytoplasm. Mitochondrion. Nucleus>nucleoplasm. Cytoplasmic, associated with mitochondria. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Metabolism |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. |
Other Clones
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Other Formats
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Unconjugated
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