MCM3AP Polyclonal Antibody (E-AB-15058)
For research use only.
| Verified Samples |
Verified Samples in WB: Hela, 293T Verified Samples in IHC: Human colon cancer, Human liver cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MCM3AP |
| Abbre | MCM3AP |
| Synonyms | 80 kDa MCM3 associated protein, 80 kDa MCM3-associated protein, FLJ44336, FLJ45306, Germinal center associated nuclear protein, KIAA0572, MAP80, MCM3 import protein, MCM3 minichromosome maintenance deficient 3 associated protein, MCM3A, Mcm3ap, Minichromosome |
| Swissprot | |
| Calculated MW | 218 kDa |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication.The protein encoded by this gene is a MCM3 binding protein.It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center.This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication.The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.This gene is expressed in the brain or in neuronal tissue.An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. |
Other Clones
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Other Formats
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Unconjugated
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