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For research use only.

Verified Samples Verified Samples in IHC: Human brain, Human prostate cancer
Dilution IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Fusion protein of human METTL7A
Abbre METTL7A
Synonyms AAM B,  AAMB,  DKFZP586A0522,  MET7A,  METTL 7A,  METTL7A,  METTL7A methlytransferase like 7A,  Methyltransferase like 7A,  Methyltransferase-like protein 7A,  Protein AAM-B,  Protein AAMB
Swissprot
Cellular Localization Lipid droplet. Endoplasmic reticulum. Membrane.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1,100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.
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Unconjugated

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