Mineralocorticoid receptor Polyclonal Antibody (E-AB-70261)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human stomach, Mouse kidney, Rat kidney |
| Dilution | IHC 1:200-1:800 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor |
| Abbre | Mineralocorticoid receptor |
| Synonyms | Aldosterone receptor, MCR, MGC133092, MLR, MR, Mineralocorticoid receptor, NR3 C2, NR3C2, NR3C2 protein, Nuclear receptor subfamily 3 group C member 2 |
| Swissprot | |
| Cellular Localization | Cytoplasm, Endoplasmic reticulum, Membrane, Nucleus. |
| Concentration | 1.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 1% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction, Cardiovascular, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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