Mini Sample Human TNF-β (Tumor Necrosis Factor Beta) ELISA Kit (E-MSEL-H0042)
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For research use only.
Product Summary
The sample size of MS series ELISA kit is only 1/4 of that of the traditional sandwich ELISA kit, which can effectively solve the problem of insufficient sample size.
| Sensitivity | 18.75 pg/mL |
| Detection Range | 31.25-2000 pg/mL |
| Sample Volume | 25 μL |
| Total Assay Time | 3 h 30 min |
| Reactivity | Human |
| Specificity | This kit recognizes Human TNF-β in samples. No significant cross-reactivity or interference between Human TNF-β and analogues was observed. |
| Recovery | 80%-120% |
| Sample Type | Serum, plasma and other biological fluids |
| Detection Method | Colorimetric method, ELISA, Sandwich |
| Assay Type | Sandwich-ELISA |
| Size | 96T / 48T / 24T / 96T*5 / 96T*10 |
| Storage | 2-8℃ |
| Expiration Date | 12 months |
Background
Human TNF-β (tumor necrosis factor β, also known as lymphotoxin α, LT-α) is a member of the TNF family with a molecular weight of about 22kDa and a high degree of homology (about 73% amino acid homology) with TNF molecules in mice and rats. TNF-β is produced primarily by activated T and B cells and acts by binding to its receptors TNFR1 and TNFR2. NF-β plays an important role in inflammation and immune responses. Studies have shown that TNF-β can activate the NF-κB signaling pathway, thereby promoting the expression of inflammatory factors
. In addition, TNF-β is also involved in the regulation of cell apoptosis, proliferation, differentiation and lipid metabolism. In studies of osteoarthritis, TNF-β has been found to promote apoptosis and inflammatory response of chondrocytes by activating the NF-κB-dependent inflammatory environment. Human TNF-β (tumor necrosis factor β, also known as lymphotoxin-α, LT-α) is a member of the TNF family with a molecular weight of approximately 22kDa. The TNF molecule has a high homology (about 73% amino acid homology) with mice and rats. TNF-β is produced primarily by activated T and B cells and acts by binding to its receptors TNFR1 and TNFR2. NF-β plays an important role in inflammation and immune responses. Studies have shown that TNF-β can activate the NF-κB signaling pathway, thereby promoting the expression of inflammatory factors
. In addition, TNF-β is also involved in the regulation of cell apoptosis, proliferation, differentiation and lipid metabolism. In studies of osteoarthritis, TNF-β has been found to promote apoptosis and inflammatory responses in chondrocytes by activating the NF-κB-dependent inflammatory environment
| Gene Alias | LTA |
| Gene ID | 4049 |
| Uniport ID | P01374 |
| Protein Alias | LTA |
| Research Area | 免疫学 , 信号传输 , 干细胞 |
| Cat.No. | Product Name | Clone No. |
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