Mouse ACV-A Antibody Pair Set (E-KAB-0648)
For research use only.
| Background |
The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition , serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion , it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore , the beta A subunit forms a homodimer , activin A , and also joins with a beta B subunit to form a heterodimer , activin AB , both of which stimulate FSH secretion. Finally , it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
|
| Synonyms |
ACV-A, Activin Beta A Beta A Homodimer
|
| Swissprot | |
| Reactivity |
Mouse
|
| Specificity |
Detects Mouse ACV-A in ELISAs
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| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
Other Clones
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