Mouse ANG2 Antibody Pair Set (E-KAB-0593)
For research use only.
| Background |
Binds to TEK/TIE2 , competing for the ANGPT1 binding site , and modulating ANGPT1 signaling.Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1.In the absence of angiogenic inducers , such as VEGF , ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression.In concert with VEGF , it may facilitate endothelial cell migration and proliferation , thus serving as a permissive angiogenic signal .Involved in the regulation of lymphangiogenesis.
|
| Synonyms |
ANGPT2, AGPT2
|
| Swissprot | |
| Reactivity |
Mouse
|
| Specificity |
Detects Mouse ANG2 in ELISAs
|
| Applications |
ELISA
|
| Storage |
-20℃
|
| Expiration date |
12 months
|
Other Clones
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