Mouse CD3/CD28 T Cell Activation Beads (MIM001A)
For research use only.
| Description | Two types of signals are required to induce T cell activation and proliferation: one is a specific antigen-stimulating signal generated by the binding of TCR/CD3 complex to the specific MHC II antigen-peptide complex on the surface of antigen-presenting cells (APCs); the other is a non-specific co-stimulatory signal generated by the interaction of co-stimulatory molecules on the surface of APCs with the corresponding receptors on the T cells, of which CD28 is one of the co-stimulatory molecule. The Mouse CD3/CD28 T Cell Activation Beads is used for activation and expansion of sorted mouse T cells or T cells from mouse spleen. |
| Feature |
activation and expansion of sorted T cells or T cells from mouse spleen |
| Form | Liquid |
| Formulation | Consists of 1×108 beads dissolved in phosphate buffered saline (PBS) |
| Intende Use | Mouse CD3/CD28 T Cell Activation Beads are made by coupling anti-CD3 and anti-CD28 antibodies to magnetic beads, which can provide the primary TCR signal and co-stimulatory signals required for T-cell activation and expansion, thus inducing T-cell activation and proliferation in vitro. For subsequent relevant experimental studies, this beads can be removed from cultured cells by using a magnetic rack. |
| Isolation Technology | Magnetic Beads |
| Reactivity | Mouse |
| Cell Type | T cells |
| Sample Type | Spleen, Lymph nodes, Whole blood, Pre-isolated T-cells |
| Clonality | Monoclonal |
| Host | Hamster |
| Usage | Add 10 µL of beads per 1×106 T cells |
| Storage | Store at 2 to 8℃.Do not freeze. |
| Shipping | Ice bag |
| Expiration Date | 12 months |
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