Mouse E-Cad Antibody Pair Set (E-KAB-0564)
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For research use only.
| Background |
Cadherins are calcium-dependent cell adhesion proteins.They preferentially interact with themselves in a homophilic manner in connecting cells , cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions , mobility and proliferation of epithelial cells.Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. Does not function as a receptor for L.monocytogenes internalin A ( InlA ) , mutating a single surface-exposed residue confers receptor activity to this protein and promotes uptake of the bacteria.
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| Synonyms |
CDH1, Arc-1, CD324, CDHE, LCAM, UVO, CAM 120/80, Epithelial Cadherin, Uvomorulin
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| Swissprot | |
| Reactivity |
Mouse
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| Specificity |
Detects Mouse E-Cad in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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