Mouse GAL3 Antibody Pair Set (E-KAB-0690)
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For research use only.
| Background |
Galectin-3 is a member of the lectin family,which includes 15 mammalian lectin members. Like all galectins,galectin-3 contains a carbohydrate recognition binding domain of about 130 amino acids that enables the specific binding of β-galactosides. This protein has been shown to be involved in cell adhesion,cell activation,chemoattraction,cell growth and differentiation,cell cycle,and apoptosis. Galectin-3 induces pro-inflammatory cytokines and inhibits Th2 type cytokine production. It chemoattracts monocytes and macrophages,and activates and degranulates basophils and mast cells. Galectin-3 has been shown to be involved in cancer,inflammation,fibrosis,heart disease,and stroke. It has also been shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure,including myofibroblast proliferation,tissue repair,inflammation,fibrogenesis,and ventricular remodeling. In addition,galectin-3 was found to contribute to tumor cell evasion of the immune system. Galectin-3 is increasingly being used as a diagnostic marker for different cancers. It can be screened for and used as a prognostic factor to predict the progression of the cancer.
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| Synonyms |
LGALS3, CBP35, GALBP, GALIG, L31, LGALS2, MAC2, Lectin, Galactoside-Binding Soluble 3
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| Swissprot | |
| Reactivity |
Mouse
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| Specificity |
Detects Mouse GAL3 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This ELISA kit applies to the in vitro quantitative determination of Mouse GAL3 concentrations in serum, plasma and other biological fluids.
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