Mouse IL-23 Antibody Pair Set (E-KAB-0572)
For research use only.
| Background |
Cytokine that can act as a growth factor for activated T and NK cells , enhance the lytic activity of NK/lymphokine-activated killer cells , and stimulate the production of IFN-gamma by resting PBMC.Associates with IL23A to form the IL-23 interleukin , a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R , activates the Jak-Stat signaling cascade , stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
|
| Synonyms |
IL-23A, IL23P19, P19, SGRF
|
| Swissprot | |
| Reactivity |
Mouse
|
| Specificity |
Detects Mouse IL-23 in ELISAs
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| Applications |
ELISA
|
| Storage |
-20℃
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| Expiration date |
12 months
|
Other Clones
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