Mouse Lptn/XCL1 Antibody Pair Set (E-KAB-0714)
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For research use only.
| Background |
XCL1,also known as lymphotactin,is an inflammatory chemokine secreted by T cells and natural killer (NK) cells. Early reports described XCL1 as a mediator of T cell and NK cell migration,but recent studies suggest a highly specialized role for XCL1 and its receptor XCR1. The XCL1-XCR1 axis has been shown to play an important role in the dendritic cell mediated cytotoxic immune response and in the formation of self-tolerance mechanisms through the development of regulatory T cells within the thymus. XCL1 also acts as a conformation-dependent inhibitor of HIV-1. Unlike other chemokines,XCL1 conformation interchanges between conserved chemokine folds and an unrelated dimeric structure under physiological conditions.
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| Synonyms |
SCYC1, LTN, ATAC, SCM-1a, SCM-1
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| Swissprot | |
| Reactivity |
Mouse
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| Specificity |
Detects Mouse Lptn/XCL1 in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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| Introduction |
This ELISA kit applies to the in vitro quantitative determination of Mouse Lptn/XCL1 concentrations in serum, plasma and other biological fluids.
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