Mouse MIP-1β Antibody Pair Set (E-KAB-0590)
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For research use only.
| Background |
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1 , HIV-2 , and simian immunodeficiency virus ( SIV ) . The processed form MIP-1-beta ( 3-69 ) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta ( 3-69 ) is also a ligand for CCR1 and CCR2 isoform B.
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| Synonyms |
CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4
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| Swissprot | |
| Reactivity |
Mouse
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| Specificity |
Detects Mouse MIP-1β in ELISAs
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| Applications |
ELISA
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| Storage |
-20℃
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| Expiration date |
12 months
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