Mouse TRAIL/TNFSF10 Antibody Pair Set (E-KAB-0562)

For research use only.
Background |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain , but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis , and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines , which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
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Synonyms |
APO2L, Apo2-L, TL2, CD253
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Swissprot | |
Reactivity |
Mouse
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Specificity |
Detects Mouse TRAIL/TNFSF10 in ELISAs
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Applications |
ELISA
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Storage |
-20℃
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Expiration date |
12 months
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Other Clones
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