MSN Polyclonal Antibody (E-AB-14222)
For research use only.
| Verified Samples |
Verified Samples in WB: 293T, A431 Verified Samples in IHC: Human thyroid cancer, Human ovarian cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MSN |
| Abbre | MSN |
| Synonyms | Epididymis luminal protein 70, HEL70, MOES, MSN/ALK fusion, Membrane organizing extension spike protein, Membrane-organizing extension spike protein, Moesin, Moesin/anaplastic lymphoma kinase fusion protein, Msn |
| Swissprot | |
| Calculated MW | 68 kDa |
| Cellular Localization | Cell membrane. Cytoplasm>cytoskeleton. Apical cell membrane. Cell projection>microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage. |
Other Clones
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Other Formats
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Unconjugated
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