MT-ND6 Polyclonal Antibody (E-AB-16622)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human cervical cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MT-ND6 |
| Abbre | MT-ND6 |
| Synonyms | MT ND6, Mitochondrially encoded NADH dehydrogenase 6, NADH Ubiquinone Oxidoreductase subunit ND6, NADH dehydrogenase subunit 6 (complex I), NADH ubiquinone oxidoreductase chain 6, NADH6, ND6, mtND6 |
| Swissprot | |
| Cellular Localization | Mitochondrion membrane, Multi-pass membrane protein. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. The significance of NADH dehydrogenase subunit 6 (ND6) is rapidly becoming increasingly apparent as many mutations leading to amino acid changes in this subunit are associated with known mitochondrial diseases. |
Other Clones
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Unconjugated
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