MTFP1 Polyclonal Antibody (E-AB-11412)
For research use only.
Verified Samples |
Verified Samples in WB: Mouse heart, Mouse muscle, Hela, Mouse liver, Mouse kidney, HepG2 Verified Samples in IHC: Human cervical cancer, Human lung cancer |
Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human MTFP1 |
Synonyms | HSPC 242, HSPC242, MTFP1, MTP 18, MTP18, Mitochondrial 18 kDa protein, Mitochondrial fission process protein 1, Mitochondrial fission protein MTP18, Mitochondrial protein 18 kDa |
Swissprot | |
Calculated MW | 18 kDa |
Cellular Localization | Mitochondrion inner membrane. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis. |
Other Clones
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Other Formats
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Unconjugated
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