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For research use only.

Verified Samples Verified Samples in WB: Mouse heart, Mouse muscle, Hela, Mouse liver, Mouse kidney, HepG2
Verified Samples in IHC: Human cervical cancer, Human lung cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human MTFP1
Synonyms HSPC 242,  HSPC242,  MTFP1,  MTP 18,  MTP18,  Mitochondrial 18 kDa protein,  Mitochondrial fission process protein 1,  Mitochondrial fission protein MTP18,  Mitochondrial protein 18 kDa
Swissprot
Calculated MW 18 kDa
Cellular Localization Mitochondrion inner membrane.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Cardiovascular,  Metabolism
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis.
Other Clones

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Unconjugated

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