MVK Polyclonal Antibody (E-AB-11414)
For research use only.
| Verified Samples |
Verified Samples in WB: Raji Verified Samples in IHC: Human thyroid cancer, Human esophagus cancer |
| Dilution | WB 1:200-1:1000, IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MVK |
| Abbre | MVK |
| Synonyms | FLJ96772, KIME, LH receptor mRNA binding protein, LRBP, MK, MVLK, Mevalonate kinase, Mevalonate kinase 1, Mevalonic aciduria, POROK3, mvk |
| Swissprot | |
| Calculated MW | 42 kDa |
| Cellular Localization | Cytoplasm. Peroxisome. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. |
Other Clones
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Other Formats
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Unconjugated
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