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For research use only.

Verified Samples Verified Samples in IHC: Human ovarian cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human MYSM1
Abbre MYSM1
Synonyms 2A-DUB,  2ADUB,  Histone H2A deubiquitinase,  Histone H2A deubiquitinase MYSM1,  KIAA1915,  MYS,  MYSM 1,  Myb like,  Myb like SWIRM and MPN domains 1,  Myb-like,  SWIRM and MPN domain containing protein,  SWIRM and MPN domains 1,  mysm1
Swissprot
Cellular Localization Nucleus.
Concentration 0.5 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones
Other Clones

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Unconjugated

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