NAE1 Polyclonal Antibody (E-AB-14592)
For research use only.
Verified Samples |
Verified Samples in WB: Human fetal muscle, Human kidney, Human liver |
Dilution | WB 1:200-1:1000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human NAE1 |
Abbre | NAE1 |
Synonyms | 59 kDa, A 116A10.1, Amyloid beta precursor , Amyloid beta precursor protein binding protein 1, Amyloid beta precursor protein binding protein 1 59kD, Amyloid beta precursor protein binding protein 1 59kDa |
Swissprot | |
Calculated MW | 60 kDa |
Cellular Localization | Cell membrane. Colocalizes with APP in lipid rafts. |
Concentration | 0.1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cell Biology, Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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