NCR2 Polyclonal Antibody (E-AB-13122)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NCR2 |
| Abbre | NCR2 |
| Synonyms | Activating NK receptor NKp44, CD336, CD336 antigen, LY95, Lymphocyte antigen 95, Lymphocyte antigen 95 (activating NK receptor, Lymphocyte antigen 95 homolog, Lymphocyte antigen 95 homolog (activating NK receptor, NK p44), Natur, dJ149M18.1, homolog of, mouse |
| Swissprot | |
| Cellular Localization | Cell membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene.NCR2 has also been designated as CD336 (cluster of differentiation 336).NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis.NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain.Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level.A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load. |
Other Clones
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Other Formats
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Unconjugated
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