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For research use only.

Verified Samples Verified Samples in WB: Mouse heart
Verified Samples in IHC: Human thyroid cancer, Human cervical cancer
Dilution WB 1:200-1:1000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human NDUFS2
Abbre NDUFS2
Synonyms 49 KD subunit,  49kDa (NA,  CI 49,  CI 49kD,  CI-49kD,  Complex 1,  Complex I 49kD,  Complex I 49kDa subunit,  Complex I-49kD,  NADH dehydrogenase (ubiquinone) Fe S protein 2,  NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa,  mitochondrial,  mitochondrial respiratory chain
Swissprot
Calculated MW 53 kDa
Cellular Localization Mitochondrion inner membrane.
Concentration 0.7 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Metabolism,  Signal Transduction,  Tags and Cell Markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Clones

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Unconjugated

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