NECTIN1 Polyclonal Antibody (E-AB-15611)
For research use only.
| Verified Samples |
Verified Samples in WB: Human cervical cancer, Human fibrous histiocytoma, Human fetal brain |
| Dilution | WB 1:200-1:1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PVRL1 |
| Abbre | PVRL1 |
| Synonyms | CD111, CD111 antigen, CLPED1, ED4, HIgR, Herpes virus entry mediator C, Herpesvirus Ig like receptor, Herpesvirus Ig-like receptor, Herpesvirus entry mediator C, HveC, MGC142031, Nectin 1, Nectin-1, OFC7, OROFACIAL CLEFT 7, ectodermal dysplasia 4 (Margarita Island type) |
| Swissprot | |
| Calculated MW | 57 kDa |
| Cellular Localization | Secreted and Cell membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Microbiology, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. |
Other Clones
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Other Formats
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Unconjugated
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