NEDD4L Polyclonal Antibody (E-AB-15252)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human prostate cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NEDD4L |
| Abbre | NEDD4L |
| Synonyms | E3 ubiquitin protein ligase NEDD4 like protein, E3 ubiquitin-protein ligase NEDD4-like, KIAA0439, NED4L, NEDD4 2, NEDD4 2c, NEDD4-2a, NEDD4.2, NEDD4L, NEDD4La, NEDD4Lb, NEDD4Lc, NEDD4Ld, NEDD4Le, NEDD4Lf, NEDD4Lg, NEDD4Lh, NEDD4b, NEDL3, Nedd4-2, Neural precursor cell expres |
| Swissprot | |
| Cellular Localization | Cytoplasm. May be recruited to exosomes by NDFIP1. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases.HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation.The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC.Single nucleotide polymorphisms in this gene may be associated with essential hypertension. |
Other Clones
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Other Formats
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Unconjugated
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