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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human ovarian cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human NEFH
Abbre NEFH
Synonyms 200 kDa neurofilament protein,  CMT2CC,  NF H,  NF-H,  NFH,  Nefh,  Neurofilament heavy polypeptide,  Neurofilament heavy polypeptide 200kDa,  Neurofilament triplet H protein
Swissprot
Cellular Localization Cytoskeleton, neurofilament, Mitochondrion, Other locations: axon, cytoplasm, myelin sheath, neurofibrillary tangle, postsynaptic density.
Concentration 0.8 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Neuroscience,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
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Unconjugated

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