NEFH Polyclonal Antibody (E-AB-16639)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human ovarian cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NEFH |
| Abbre | NEFH |
| Synonyms | 200 kDa neurofilament protein, CMT2CC, NF H, NF-H, NFH, Nefh, Neurofilament heavy polypeptide, Neurofilament heavy polypeptide 200kDa, Neurofilament triplet H protein |
| Swissprot | |
| Cellular Localization | Cytoskeleton, neurofilament, Mitochondrion, Other locations: axon, cytoplasm, myelin sheath, neurofibrillary tangle, postsynaptic density. |
| Concentration | 0.8 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. |
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