NEFH Polyclonal Antibody (E-AB-16639)
For research use only.
Verified Samples |
Verified Samples in IHC: Human colon cancer, Human ovarian cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human NEFH |
Abbre | NEFH |
Synonyms | 200 kDa neurofilament protein, CMT2CC, NF H, NF-H, NFH, Nefh, Neurofilament heavy polypeptide, Neurofilament heavy polypeptide 200kDa, Neurofilament triplet H protein |
Swissprot | |
Cellular Localization | Cytoskeleton, neurofilament, Mitochondrion, Other locations: axon, cytoplasm, myelin sheath, neurofibrillary tangle, postsynaptic density. |
Concentration | 0.8 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Neuroscience, Signal transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. |
Other Clones
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Other Formats
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Unconjugated
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