NLRP10 Polyclonal Antibody (E-AB-16648)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human gastric cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NLRP10 |
| Abbre | NLRP10 |
| Synonyms | CLR11.1, LRR and PYD domains containing protein 10, LRR and PYD domains-containing protein 10, NACHT, NAL10, NALP10, NLR family, NOD8, Nlrp10, Nucleotide-binding oligomerization domai, leucine rich repeat and PYD containing 10, pyrin domain containing 10 |
| Swissprot | |
| Cellular Localization | Plasma Membrane, extrinsic component of plasma membrane, Other locations: cytoplasm. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell biology, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. |
Other Clones
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Other Formats
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Unconjugated
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