NLRP4 Polyclonal Antibody (E-AB-16628)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human prostate cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NLRP4 |
| Abbre | NLRP4 |
| Synonyms | CLR19.5, CT58, Cancer/testis antigen 58, FLJ32126, LRR and PYD containing protein 4, LRR and PYD domains-containing protein 4, NACHT, NALP4, NLR family, NLRP4, Nucleotide binding oligome, leucine rich repeat and PYD containing 4, pyrin domain containing 4 |
| Swissprot | |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell biology, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes |
Other Clones
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Other Formats
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Unconjugated
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