NLRP7 Polyclonal Antibody (E-AB-16254)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human brain |
| Dilution | IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NLRP7 |
| Abbre | NLRP7 |
| Synonyms | CLR19.4, FLJ94610, HYDM, LRR and PYD containing protein 7, LRR and PYD domains containing protein 7, LRR and PYD domains-containing protein 7, MGC126470, MGC126471, NACHT, NALP7, NLR family, leucine rich repeat and PYD containing 7, pyrin doma |
| Swissprot | |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell biology, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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