NPHS2 Polyclonal Antibody (E-AB-16657)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human thyroid cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human NPHS2 |
| Abbre | NPHS2 |
| Synonyms | NPHS2, NPHS2 gene, Nephrosis 2, PDCN, PODO, Podocin, SRN1, idiopathic, nephrosis 2, steroid resistant, steroid resistant (podocin) |
| Swissprot | |
| Cellular Localization | Cell membrane. |
| Concentration | 1.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology, Signal transduction, Tags & Cell Markers |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. |
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