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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human thyroid cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human NPHS2
Abbre NPHS2
Synonyms NPHS2,  NPHS2 gene,  Nephrosis 2,  PDCN,  PODO,  Podocin,  SRN1,  idiopathic,  nephrosis 2,  steroid resistant,  steroid resistant (podocin)
Swissprot
Cellular Localization Cell membrane.
Concentration 1.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell biology,  Signal transduction,  Tags and Cell markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
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Unconjugated

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