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For research use only.

Verified Samples Verified Samples in WB: Hela, Human prostate, A172, Mouse liver
Verified Samples in IHC: Human breast cancer, Human esophagus cancer
Dilution WB 1:1000-1:5000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human NDNL2
Abbre NDNL2
Synonyms 1,  HCA4,  MAGE-G1 antigen,  MAGEG1,  MAGEL3,  NSE3,  NSMCE3,  family G,  hepatocellular carcinoma-associated protein 4,  hepatocellular carcinoma-associated protein HCA4,  melanoma antigen,  melanoma-associated antigen G1,  necdin-like 2,  necdin-like gene 2,  necdin-like protein 2
Swissprot
Calculated MW 34 kDa
Cellular Localization Cytoplasmic and Nuclear.
Concentration 1.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).
Other Clones

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Unconjugated

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