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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human liver cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human OLR1
Abbre OLR1
Synonyms C-type lectin domain family 8 member A,  CLEC8A,  Lectin like oxLDL receptor 1,  Lectin like oxidized LDL receptor 1,  Lectin type oxidized LDL receptor 1,  Lectin-like oxLDL receptor 1,  Lectin-like oxidized LDL receptor 1,  Lectin-type oxidized LDL rece,  hLOX 1,  hLOX-1
Swissprot
Cellular Localization Cell membrane. Secreted. A secreted form also exists.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular,  Metabolism
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
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Unconjugated

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