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For research use only.

Verified Samples Verified Samples in WB: Mouse liver
Verified Samples in IHC: Human tonsil
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human OTC
Abbre OTC
Synonyms EC 2.1.3.3,  MGC129967,  MGC129968,  MGC138856,  OCTD,  OTC,  OTCase,  Ornithine carbamoyltransferase,  Ornithine carbamoyltransferase mitochondrial,  Ornithine transcarbamylase,  Otc,  mitochondrial
Swissprot
Calculated MW 40 kDa
Cellular Localization Mitochondrion matrix.
Concentration 0.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal Transduction,  Tags and Cell Markers
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This nuclear gene encodes a mitochondrial matrix enzyme.Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia.Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Other Clones

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Unconjugated

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