OXA Polyclonal Antibody (D-AB-10449L)

For research use only.
Verified Samples |
Verified Samples in IHC: Mouse brain, Rat brain |
Dilution | IHC 1:1000-1:2000 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Recombinant Human OXA protein expressed by E.coli |
Abbre | OXA |
Synonyms | HCRT, Hypocretin, Hypocretin neuropeptide precursor, OX, Orexin precursor, PPORX, PPOX, Prepro-orexin, Preprohypocretin |
Swissprot | |
Cellular Localization | Mitochondrion inner membrane. |
Concentration | 1 mg/mL |
Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
Purification Method | Antigen Affinity Purification |
Research Areas | Biochemicals, Metabolism, Signal Transduction, Neuroscience, Tags & Cell Markers, Cancer, Cardiovascular, Cell Biology, Immunology, Microbiology |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | OXA1L (OXA1L Mitochondrial Inner Membrane Protein) is a Protein Coding gene. The OXA1L gene,located on 14q11.2,is conserved in chimpanzee,Rhesus monkey,dog,and cow,etc. This gene encodes an evolutionarily conserved protein that is localized to the inner mitochondrial membrane. The encoded protein is essential for the translocation of the N-terminal tail of subunit 2 of cytochrome c oxidase and is involved in the assembly of the cytochrome c oxidase and ATPase complexes of the mitochondrial respiratory chain. In humans,the mitochondrial inner membrane protein Oxa1L is involved in the biogenesis of membrane proteins and facilitates the insertion of both mitochondrial- and nuclear-encoded proteins from the mitochondrial matrix into the inner membrane. The C-terminal approximately 100-amino acid tail of Oxa1L (Oxa1L-CTT) binds to mitochondrial ribosomes and plays a role in the co-translational insertion of mitochondria-synthesized proteins into the inner membrane. |
Other Clones
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Other Formats
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Unconjugated
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