PAK2 Polyclonal Antibody (E-AB-10521)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PAK2 |
| Abbre | PAK2 |
| Synonyms | C-t-PAK2, CB422, EC 2.7.11.1, Gamma PAK, Gamma-PAK, Kinase, hPAK65, p21 (CDKN1A) activated kinase 2, p21 (CDKN1A)-activated kinase 2a, p21 activated kinase 2, p21 protein (Cdc42/Rac)-activated kinase 2, p21 protein Cdc42 Rac activated kinase 2, p21-activated kinase 2 |
| Swissprot | |
| Cellular Localization | Cytoplasm and Nucleus. Cytoplasm>perinuclear region. Membrane. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Microbiology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling.The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities.The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. |
Other Clones
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