For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human esophagus cancer |
| Dilution | IHC 1:30-1:150 |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PCDHGB5 |
| Abbre | PCDHGB5 |
| Synonyms | PCDH gamma B5, PCDH-GAMMA-B5, PCDHGB 5, Protocadherin gamma B5, Protocadherin gamma subfamily B 5 |
| Swissprot | |
| Cellular Localization | Cell membrane, Single-pass type I membrane protein. |
| Concentration | 1.4 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Neuroscience, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. |
Other Clones
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