PDCD6 Polyclonal Antibody (E-AB-14287)
For research use only.
| Verified Samples |
Verified Samples in WB: Jurkat, Hela, Human fetal lung, A549 Verified Samples in IHC: Human thyroid cancer |
| Dilution | WB 1:200-1:1000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PDCD6 |
| Abbre | PDCD6 |
| Synonyms | AIP1, ALG 2, ALG-2-interacting protein 1, ALG2, ALIX, Apoptosis linked gene 2, Apoptosis linked gene 2 protein, Apoptosis-linked gene 2 protein, FLJ42309, FLJ46208, Hp95, KIAA1375, MA 3, MA3, MGC111017, MGC119050, MGC9123, PDCD 6, PDCD6, PEF 1B, PEF1B, Pdcd6, Probable calcium |
| Swissprot | |
| Calculated MW | 22 kDa |
| Cellular Localization | Nucleus membrane. Endoplasmic reticulum membrane. Nucleus. Endosome. Interaction with RBM22 induces relocalization from the cytoplasm to the nucleus. Translocated from the cytoplasm to the nucleus after heat shock cell treatment. Accumulates in cytoplasmic vesicle-like organelles after heat shock treatment, which may represent stress granules. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. |
Other Clones
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Other Formats
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Unconjugated
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